Abstract | PURPOSE: METHODS: The medical records of all neonates with CDH treated in our institution between 2004 and 2011 were reviewed. The presence of a hernia sac was confirmed at the time of surgical repair or at autopsy. Data were analyzed using parametric and non-parametric tests where appropriate. Multivariable regression and survival analyses were applied. RESULTS: Of 148 neonates treated for CDH, 107 (72%) had isolated CDH and 30 (20%) had a hernia sac. Infants with a hernia sac had significantly lower need for ECMO, patch repair, supplemental oxygen at 30 days of life, and shorter duration of mechanical ventilation and hospital stay. Ninety-three patients had prenatal imaging. The mean observed-to-expected total fetal lung volume in the sac group was higher throughout gestation. Although a greater percentage of sac patients had liver herniation as a dichotomous variable, the amount of herniated liver (%LH and LiTR) was significantly lower in the presence of a hernia sac. CONCLUSION:
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Authors | Irving J Zamora, Darrell L Cass, Timothy C Lee, Stephen Welty, Christopher I Cassady, Amy R Mehollin-Ray, Sara C Fallon, Rodrigo Ruano, Michael A Belfort, Oluyinka O Olutoye |
Journal | Journal of pediatric surgery
(J Pediatr Surg)
Vol. 48
Issue 6
Pg. 1165-71
(Jun 2013)
ISSN: 1531-5037 [Electronic] United States |
PMID | 23845602
(Publication Type: Evaluation Study, Journal Article)
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Copyright | Copyright © 2013 Elsevier Inc. All rights reserved. |
Topics |
- Cohort Studies
- Combined Modality Therapy
- Extracorporeal Membrane Oxygenation
- Female
- Fetal Organ Maturity
- Hernia, Diaphragmatic
(embryology, mortality, pathology, therapy)
- Hernias, Diaphragmatic, Congenital
- Herniorrhaphy
- Humans
- Infant, Newborn
- Length of Stay
(statistics & numerical data)
- Linear Models
- Logistic Models
- Lung
(embryology)
- Male
- Multivariate Analysis
- Pregnancy
- Prenatal Diagnosis
- Retrospective Studies
- Survival Analysis
- Treatment Outcome
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