Abstract | PURPOSE: To compare intraocular pressure (IOP) measurements before and after laser in situ keratomileusis ( LASIK) using a femtosecond laser for flap creation, and to identify factors that may influence the preoperative and postoperative IOP, and the change in IOP after LASIK. METHODS: Forty eyes from 20 patients who underwent treatment for myopia using a femtosecond laser for flap creation were enrolled in this study. The IOP and corneal biomechanical markers were prospectively measured preoperatively and 1 month after LASIK with Goldmann applanation tonometry ( GAT) and the ocular response analyzer (ORA). Manifest refraction spherical equivalent, central corneal thickness, ablation depth, and mean corneal curvature (K reading) were also recorded. RESULTS: After LASIK, there was a significant reduction in the IOP measurement with respect to the corneal-compensated intraocular pressure (IOPcc) (Δ=-0.67±2.07 mm Hg), Goldmann-correlated pressure (IOPg) (Δ=-3.92±2.19 mm Hg), and GAT (Δ=-2.6±2.51). Multiple regression analysis revealed that the corneal hysteresis (CH) and corneal resistance factor (CRF) are statistically significant predictors of IOPcc, IOPg, and GAT (P<0.000). In this analysis, the preoperative manifest refraction spherical equivalent, CH, and CRF were significant predictors of ΔIOPcc (adjusted R²=0.401) and ΔIOPg (adjusted R²=0.386). The preoperative SE and central corneal thickness significantly predicted ΔGAT (adjusted R²=0.464). CONCLUSIONS: ORA provides a more complete measurement of IOP after LASIK with a femtosecond laser than GAT because ORA provides greater knowledge of the corneal biomechanics in terms of CH and CRF.
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Authors | Jonghoon Shin, Tae Won Kim, Soo Jeong Park, Min Yoon, Ji Woong Lee |
Journal | Journal of glaucoma
(J Glaucoma)
Vol. 24
Issue 3
Pg. 195-201
(Mar 2015)
ISSN: 1536-481X [Electronic] United States |
PMID | 23807345
(Publication Type: Journal Article, Research Support, Non-U.S. Gov't)
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Topics |
- Adolescent
- Adult
- Biomechanical Phenomena
- Cornea
(physiology)
- Corneal Pachymetry
- Corneal Stroma
(surgery)
- Elasticity
(physiology)
- Female
- Humans
- Intraocular Pressure
(physiology)
- Keratomileusis, Laser In Situ
(methods)
- Lasers, Excimer
(therapeutic use)
- Male
- Myopia
(physiopathology, surgery)
- Postoperative Period
- Surgical Flaps
- Tonometry, Ocular
(methods)
- Young Adult
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