Cytomegalovirus polyradiculopathy of late onset in a young renal transplant recipient.

Abstract

Although cytomegalovirus (CMV) disease in CMV IgM/IgG-negative renal transplant recipients from CMV-positive donors (D+/R-) can occur after discontinuation of prophylaxis treatment as a flu-like syndrome or tissue invasive disease, involvement of the central nervous system is rare. Here, we report a case of CMV polyradiculopathy 6 months after renal transplantation that presented as a Guillain-Barre like syndrome and was successfully treated with foscarnet. This case highlights an uncommon aspect of CMV invasive disease which we should keep in mind in CMV (D+/R-) renal transplant recipients.

• Authors: Marios Papasotiriou, Evangelos Papachristou, Markos Marangos, Maria Koukoulaki, Eirini Savvidaki, Pantelitsa Kalliakmani, Dimitrios S Goumenos
• Journal: Clinical nephrology (Clin Nephrol) Vol. 80 Issue 1 Pg. 75-8 (Jul 2013) ISSN: 0301-0430 [Print] Germany
• PMID: 23803598 (Publication Type: Case Reports, Journal Article)

Chemical References

• Antiviral Agents
• Foscarnet
• Valganciclovir
• Ganciclovir

Topics

• Adult
• Antiviral Agents (therapeutic use)
• Cytomegalovirus Infections (complications, drug therapy)
• Foscarnet (therapeutic use)
• Ganciclovir (analogs & derivatives, therapeutic use)
• Humans
• Kidney Transplantation (adverse effects)
• Magnetic Resonance Imaging
• Polyradiculopathy (diagnosis, virology)
• Time Factors
• Valganciclovir