Tumors of central and peripheral nervous system associated with inherited genetic syndromes.

Abstract

There are several genetic syndromes that predispose to the development of tumors of the nervous system. In the present study, we provide a review of the tumors that are associated with neurofibromatosis type 1, neurofibromatosis type 2, tuberous sclerosis complex, von Hippel-Lindau disease, Li-Fraumeni syndrome, Cowden disease, Turcot syndrome, nevoid basal cell carcinoma syndrome (Gorlin syndrome) and rhabdoid predisposition syndrome, which are the most common.

• Authors: Kalliopi Stefanaki, George A Alexiou, Christina Stefanaki, Neofytos Prodromou
• Journal: Pediatric neurosurgery (Pediatr Neurosurg) Vol. 48 Issue 5 Pg. 271-85 ( 2012) ISSN: 1423-0305 [Electronic] Switzerland
• PMID: 23796843 (Publication Type: Journal Article, Review)
• Copyright: Copyright © 2013 S. Karger AG, Basel.

Topics

• Animals
• Brain Neoplasms (diagnosis, epidemiology, genetics)
• Central Nervous System Neoplasms (diagnosis, epidemiology, genetics)
• Colorectal Neoplasms (diagnosis, epidemiology, genetics)
• Humans
• Li-Fraumeni Syndrome (diagnosis, epidemiology, genetics)
• Neoplastic Syndromes, Hereditary (diagnosis, epidemiology, genetics)
• Neurofibromatosis 1 (diagnosis, epidemiology, genetics)
• Peripheral Nervous System Neoplasms (diagnosis, epidemiology, genetics)
• Syndrome
• Tuberous Sclerosis (diagnosis, epidemiology, genetics)
• von Hippel-Lindau Disease (diagnosis, epidemiology, genetics)