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Virchow lymph node metastatic recurrence of sigmoid colon cancer with severe lymph node metastases successfully treated using systemic chemotherapy combined with radiotherapy.

Abstract
Metastatic recurrence of colon cancer in the left supraclavicular lymph node (Virchow lymph node) is rare, and to date there are no reports on radiotherapy as treatment. We report on a case of metastatic recurrence of sigmoid colon cancer in the Virchow lymph node with severe lymph node metastases successfully treated with a combined modality therapy of systemic chemotherapy and radiotherapy. The case is of a 58-year-old man, who underwent sigmoid excision and lymph node excision, and subsequently received systemic chemotherapy. After left supraclavicular lymph node recurrence appeared he later received radiotherapy. Complete response was achieved, and there has been no further recurrence, to date, 10 months after the radiotherapy. Radiotherapy was effective as a local treatment, and local control of distant metastasis of colonic cancer may lead to a good prognosis.
AuthorsTakafumi Ohchi, Yoshito Akagi, Tetsushi Kinugasa, Yoshiaki Ishibashi, Natsuki Tanaka, Shinya Fujino, Shiro Kibe, Kotaro Yuge, Teruo Sasatomi, Tomoaki Mizobe, Yosuke Oka, Kawang Dae Hong, Kazuo Shirouzu
JournalAnticancer research (Anticancer Res) Vol. 33 Issue 7 Pg. 2935-40 (Jul 2013) ISSN: 1791-7530 [Electronic] Greece
PMID23780983 (Publication Type: Case Reports, Journal Article)
Chemical References
  • Antibodies, Monoclonal, Humanized
  • Organoplatinum Compounds
  • Oxaliplatin
  • Deoxycytidine
  • Bevacizumab
  • Capecitabine
  • Fluorouracil
Topics
  • Antibodies, Monoclonal, Humanized (administration & dosage)
  • Antineoplastic Combined Chemotherapy Protocols (therapeutic use)
  • Bevacizumab
  • Capecitabine
  • Chemoradiotherapy
  • Clavicle (pathology)
  • Deoxycytidine (administration & dosage, analogs & derivatives)
  • Fluorouracil (administration & dosage, analogs & derivatives)
  • Humans
  • Lymphatic Metastasis
  • Male
  • Middle Aged
  • Neoplasm Recurrence, Local (pathology, therapy)
  • Organoplatinum Compounds (administration & dosage)
  • Oxaliplatin
  • Prognosis
  • Remission Induction
  • Sigmoid Neoplasms (secondary, therapy)

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