Descriptions and correlates of salivary cotinine in individuals with schizophrenia spectrum disorders.

Abstract

The purpose of this study was to describe the procedure and results of salivary cotinine testing and to examine correlations between cotinine levels, self-reported smoking behavior, and other demographic variables in outpatients with schizophrenia spectrum disorders (SSDs). Twenty-one participants completed salivary cotinine measures. Sixteen reported smoking cigarettes (mean = 1.2 packs per day; SD = 0.8; range = 0.25 to 3.0) for a mean of 27.4 years (SD = 16.3 years, range = 1 to 46 years). Age was significantly positively correlated with self-report of packs smoked per day (r = 0.52; p = 0.04) and years smoked (r = 0.63; p = 0.02). There was no clear pattern of relationship between salivary cotinine level and self-reported smoking behavior. This pilot study adds to a small body of literature describing salivary cotinine measures in individuals with SSDs, yet further investigation is warranted to definitively determine the utility of this objective measure of nicotine use.

• Authors: Lora Humphrey Beebe, Carla Renee Parker
• Journal: Journal of psychosocial nursing and mental health services (J Psychosoc Nurs Ment Health Serv) Vol. 51 Issue 8 Pg. 33-8 (Aug 2013) ISSN: 0279-3695 [Print] United States
• PMID: 23758225 (Publication Type: Journal Article, Research Support, Non-U.S. Gov't)
• Copyright: Copyright 2013, SLACK Incorporated.

Chemical References

• Cotinine

Topics

• Adult
• Cotinine (metabolism)
• Female
• Humans
• Male
• Middle Aged
• Pilot Projects
• Saliva (metabolism)
• Schizophrenia (metabolism)
• Smoking (metabolism)
• Young Adult