Abstract | PURPOSE: The study aims were (1) to determine whether baseline measures-including the Body Mass Index, Airflow Obstruction, Dyspnea, and Exercise Capacity (BODE) index; Age, Dyspnea, and Airflow Obstruction ( ADO) index; physical activity; comorbidities (cardiac, metabolic, or musculoskeletal disease); and the number of hospitalizations over the previous 12 months-can predict responders in 6-minute walk distance (6MWD) following pulmonary rehabilitation (PR) and (2) to determine whether different methods in defining improvement in 6MWD affected identifying responders to PR. METHODS: All participants with chronic obstructive pulmonary disease who attended PR at our institution between 2004 and 2009 were evaluated. A participant was classified as a responder with improvement in 6MWD (≥25 m or ≥2 SD of this dataset coefficient of repeatability). RESULTS: A total of 203 participants (mean age, 68.2 ± 8.7 years; mean predicted forced expiratory volume in 1 second, 52.5 ± 22.4%) were analyzed. One hundred twenty participants (59.1%) had a comorbidity categorized as cardiac, metabolic, or musculoskeletal disease. The binary logistic regression models showed that younger participants (P ≤ .015) and, when using the coefficient of repeatability method (≥60.9 m), participants with metabolic disease (P = .040) were the only independent predictors of response. No other measure, including participant BODE or ADO index scores, contributed to either model. CONCLUSION: Identifying responders in exercise capacity following PR remains difficult, with only age and participants with metabolic disease identified as independent predictors.
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Authors | James R Walsh, Zoe J McKeough, Norman R Morris, Angela T Chang, Stephanie T Yerkovich, Helen E Seale, Jenny D Paratz |
Journal | Journal of cardiopulmonary rehabilitation and prevention
(J Cardiopulm Rehabil Prev)
2013 Jul-Aug
Vol. 33
Issue 4
Pg. 249-56
ISSN: 1932-751X [Electronic] United States |
PMID | 23748375
(Publication Type: Comparative Study, Journal Article)
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Topics |
- Age Factors
- Aged
- Body Mass Index
- Exercise Therapy
(methods)
- Exercise Tolerance
(physiology)
- Female
- Follow-Up Studies
- Humans
- Male
- Metabolic Syndrome
(epidemiology, etiology)
- Motor Activity
(physiology)
- Prevalence
- Prognosis
- Pulmonary Disease, Chronic Obstructive
(complications, rehabilitation)
- Queensland
(epidemiology)
- Retrospective Studies
- Risk Factors
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