Abstract |
In era of systemic chemotherapy for colorectal liver metastasis (CLM), role of hepatic intraarterial infusion chemotherapy (HAIC) remains important. We examined treatment effects of HAIC in 36 patients with non-resectable CLM using 5-FU or CPT-11. Tumor response was complete response (CR) in 4, partial response (PR) in 19, stable disease (SD) in 6, and progressive disease (PD) in 7. Tumor control rate was 81% and response rate was 64%. Six patients showed catheter-related complications. Median survival period was 62 months in CR, and 25 with PR. HAIC has a major impact in high chemotherapy response and prolonging survival.
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Authors | Atsushi Nanashima, Hiroaki Takeshita, Takafumi Abo, Kazuo Tou, Kenji Tanaka, Daisuke Fukuda, Masaki Kunizaki, Shigekazu Hidaka, Terumitsu Sawai |
Journal | Journal of gastrointestinal oncology
(J Gastrointest Oncol)
Vol. 4
Issue 2
Pg. 164-72
(Jun 2013)
ISSN: 2078-6891 [Print] China |
PMID | 23730512
(Publication Type: Journal Article)
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