Abstract | PURPOSE: BASIC PROCEDURES: From 2006 to 2011, we retrospectively analyzed 202 patients 65 years or younger with a definite diagnosis of rhabdomyolysis and serum creatinine phosphokinase levels greater than 1000 IU/L. The related clinical factors were analyzed in the patients with ARF caused by rhabdomyolysis. In addition, receiver operating characteristic curves were used to establish the appropriate cutoff values of serum biomarkers in predicting ARF. MAIN FINDINGS: PRINCIPAL CONCLUSIONS: Age, dark urine, etiologies, serum levels of blood urea nitrogen, creatinine and potassium, and initial and peak serum myoglobin levels may serve as important factors in predicting ARF in patients with rhabdomyolysis. We suggest that the appropriate cutoff value of initial serum myoglobin for predicting ARF is 600 ng/mL.
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Authors | Chun-Yu Chen, Yan-Ren Lin, Lu-Lu Zhao, Wen-Chieh Yang, Yu-Jun Chang, Han-Ping Wu |
Journal | The American journal of emergency medicine
(Am J Emerg Med)
Vol. 31
Issue 7
Pg. 1062-6
(Jul 2013)
ISSN: 1532-8171 [Electronic] United States |
PMID | 23702059
(Publication Type: Evaluation Study, Journal Article, Research Support, Non-U.S. Gov't)
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Copyright | Copyright © 2013 Elsevier Inc. All rights reserved. |
Chemical References |
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Topics |
- Acute Kidney Injury
(blood, diagnosis, etiology, therapy)
- Adolescent
- Adult
- Aged
- Biomarkers
(blood)
- Child
- Child, Preschool
- Decision Support Techniques
- Emergency Service, Hospital
- Female
- Humans
- Infant
- Infant, Newborn
- Logistic Models
- Male
- Middle Aged
- ROC Curve
- Renal Replacement Therapy
- Retrospective Studies
- Rhabdomyolysis
(blood, complications)
- Risk Factors
- Young Adult
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