Abstract | PURPOSE: DESIGN: Randomized, prospective, patient- and examiner-masked clinical trial with intraindividual comparison. METHODS: One hundred patients with bilateral age-related cataract (200 eyes) had standard cataract surgery with implantation of an iMics1 NY-60 IOL (Hoya Corp) in one eye and an AcrySof SN60WF IOL (Alcon Laboratories) in the other eye. Follow-up examinations were performed at 1 week and 3 years. Digital retroillumination images were obtained of each eye. The main outcome measure was PCO score (scale, 0 to 10) assessed subjectively at the slit lamp and objectively using automated image analysis software (Automated Quantification of After- Cataract) 3 years after surgery. RESULTS: The objective PCO score (mean ± standard deviation) was 3.0 ± 2.0 for the iMics1 NY-60 IOL and 1.9 ± 1.4 for the AcrySof SN60WF IOL (P < .001). Three years after surgery, 35.6% of patients underwent a neodymium: yttrium-aluminum-garnet capsulotomy in the iMics1 NY-60 eye and 13.7% underwent a capsulotomy in the AcrySof SN60WF eye (P = .001). There was no statistically significant difference in best-corrected visual acuity, rhexis-IOL overlap, capsular folds, or anterior capsule opacification. Glistening formations were found in no iMics1 NY-60 IOLs, but in 97% of the AcrySof SN60WF IOLs. CONCLUSIONS: Comparison of 2 sharp-edged single-piece IOLs of similar design and hydrophobic acrylic material indicated a statistically significant difference in PCO and neodymium: yttrium-aluminum-garnet capsulotomy rate 3 years after surgery.
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Authors | Christina Leydolt, Sabine Schriefl, Eva Stifter, Alexandra Haszcz, Rupert Menapace |
Journal | American journal of ophthalmology
(Am J Ophthalmol)
Vol. 156
Issue 2
Pg. 375-381.e2
(Aug 2013)
ISSN: 1879-1891 [Electronic] United States |
PMID | 23677137
(Publication Type: Comparative Study, Journal Article, Randomized Controlled Trial)
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Copyright | Copyright © 2013 Elsevier Inc. All rights reserved. |
Chemical References |
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Topics |
- Acrylic Resins
- Aged
- Capsule Opacification
(diagnosis, etiology, surgery)
- Double-Blind Method
- Female
- Humans
- Image Processing, Computer-Assisted
- Laser Therapy
- Lasers, Solid-State
(therapeutic use)
- Lens Implantation, Intraocular
- Lenses, Intraocular
(adverse effects)
- Male
- Phacoemulsification
- Posterior Capsule of the Lens
(pathology)
- Prospective Studies
- Prosthesis Design
- Visual Acuity
(physiology)
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