HOMEPRODUCTSCOMPANYCONTACTFAQResearchDictionaryPharmaSign Up FREE or Login

Posterior capsule opacification with the iMics1 NY-60 and AcrySof SN60WF 1-piece hydrophobic acrylic intraocular lenses: 3-year results of a randomized trial.

AbstractPURPOSE:
To compare the intensity of posterior capsule opacification (PCO) 3 years after implantation of 2 different 1-piece foldable hydrophobic acrylic intraocular lenses (IOLs).
DESIGN:
Randomized, prospective, patient- and examiner-masked clinical trial with intraindividual comparison.
METHODS:
One hundred patients with bilateral age-related cataract (200 eyes) had standard cataract surgery with implantation of an iMics1 NY-60 IOL (Hoya Corp) in one eye and an AcrySof SN60WF IOL (Alcon Laboratories) in the other eye. Follow-up examinations were performed at 1 week and 3 years. Digital retroillumination images were obtained of each eye. The main outcome measure was PCO score (scale, 0 to 10) assessed subjectively at the slit lamp and objectively using automated image analysis software (Automated Quantification of After-Cataract) 3 years after surgery.
RESULTS:
The objective PCO score (mean ± standard deviation) was 3.0 ± 2.0 for the iMics1 NY-60 IOL and 1.9 ± 1.4 for the AcrySof SN60WF IOL (P < .001). Three years after surgery, 35.6% of patients underwent a neodymium:yttrium-aluminum-garnet capsulotomy in the iMics1 NY-60 eye and 13.7% underwent a capsulotomy in the AcrySof SN60WF eye (P = .001). There was no statistically significant difference in best-corrected visual acuity, rhexis-IOL overlap, capsular folds, or anterior capsule opacification. Glistening formations were found in no iMics1 NY-60 IOLs, but in 97% of the AcrySof SN60WF IOLs.
CONCLUSIONS:
Comparison of 2 sharp-edged single-piece IOLs of similar design and hydrophobic acrylic material indicated a statistically significant difference in PCO and neodymium:yttrium-aluminum-garnet capsulotomy rate 3 years after surgery.
AuthorsChristina Leydolt, Sabine Schriefl, Eva Stifter, Alexandra Haszcz, Rupert Menapace
JournalAmerican journal of ophthalmology (Am J Ophthalmol) Vol. 156 Issue 2 Pg. 375-381.e2 (Aug 2013) ISSN: 1879-1891 [Electronic] United States
PMID23677137 (Publication Type: Comparative Study, Journal Article, Randomized Controlled Trial)
CopyrightCopyright © 2013 Elsevier Inc. All rights reserved.
Chemical References
  • Acrylic Resins
Topics
  • Acrylic Resins
  • Aged
  • Capsule Opacification (diagnosis, etiology, surgery)
  • Double-Blind Method
  • Female
  • Humans
  • Image Processing, Computer-Assisted
  • Laser Therapy
  • Lasers, Solid-State (therapeutic use)
  • Lens Implantation, Intraocular
  • Lenses, Intraocular (adverse effects)
  • Male
  • Phacoemulsification
  • Posterior Capsule of the Lens (pathology)
  • Prospective Studies
  • Prosthesis Design
  • Visual Acuity (physiology)

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.
Realize the full power of the drug-disease research graph!


Choose Username:
Email:
Password:
Verify Password:
Enter Code Shown: