[IgA antibodies in exogenous allergic alveolitis are more specific than IgG antibodies].

Abstract

Nineteen sera from patients suffering from extrinsic allergic alveolitis (bird fancier's lung, farmer's lung) and 19 sera from asymptomatic persons demonstrating IgG-antibodies were examined for IgA-antibodies against pigeon serum, Micropolyspora faeni and Aspergillus fumigatus. The IgA-antibodies against pigeon serum and Micropolyspora faeni were less of ten false-positive than the corresponding IgG-antibodies. Hence the IgA-antibodies were more specific than the IgG-antibodies. However, the sensitivity of the IgA-antibodies was lower than that of the IgG-antibodies. On the other hand IgA-antibodies against Aspergillus fumigatus were scarcely more specific than the corresponding IgG-antibodies against pigeon and M. faeni. It would thus seem that IgA-antibodies can supplement the IgG-serodiagnosis of extrinsic allergic alveolitis.

• Authors: J Sennekamp, M Rust, R Kroidl, M Spyra
• Journal: Pneumologie (Stuttgart, Germany) (Pneumologie) Vol. 44 Suppl 1 Pg. 522-3 (Feb 1990) ISSN: 0934-8387 [Print] Germany
• Vernacular Title: IgA-Antikörper bei exogen allergischer Alveolitis sind spezifischer als IgG-Antikörper.
• PMID: 2367456 (Publication Type: English Abstract, Journal Article)

Chemical References

• Immunoglobulin A
• Immunoglobulin G

Topics

• Alveolitis, Extrinsic Allergic (diagnosis)
• Aspergillosis, Allergic Bronchopulmonary (diagnosis)
• Bird Fancier's Lung (diagnosis)
• Humans
• Immunoglobulin A (analysis)
• Immunoglobulin G (analysis)