Abstract | PURPOSE: METHODS: 41 Patients were randomised to SEMS followed by brachytherapy, 8 Gy×3 (n=21) or brachytherapy alone, 8 Gy×3 (n=20). Change in dysphagia and pain three and seven weeks after randomisation (FU1 and FU2) was assessed by patient-reported outcome. Dysphagia, other symptoms and health-related quality of life were assessed every four weeks thereafter. The study was closed before the estimated patient-number was reached due to slow recruitment. RESULTS: Patients receiving SEMS followed by brachytherapy had significantly improved dysphagia at FU1 compared to patients receiving brachytherapy alone (n=35). Difference in pain was not observed. At FU2, patients in both arms (n=21) had less dysphagia. Four patients in the combined treatment arm experienced manageable complications, no complications occurred after brachytherapy alone. CONCLUSION:
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Authors | Cecilie Delphin Amdal, Anne-Birgitte Jacobsen, Berit Sandstad, Trond Warloe, Kristin Bjordal |
Journal | Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology
(Radiother Oncol)
Vol. 107
Issue 3
Pg. 428-33
(Jun 2013)
ISSN: 1879-0887 [Electronic] Ireland |
PMID | 23647761
(Publication Type: Clinical Trial, Phase III, Journal Article, Randomized Controlled Trial, Research Support, Non-U.S. Gov't)
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Copyright | Copyright © 2013 Elsevier Ireland Ltd. All rights reserved. |
Topics |
- Aged
- Aged, 80 and over
- Brachytherapy
(adverse effects)
- Deglutition Disorders
(etiology)
- Esophageal Neoplasms
(mortality, psychology, radiotherapy)
- Female
- Humans
- Male
- Middle Aged
- Palliative Care
- Quality of Life
- Stents
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