Central corneal regularization--optimization of uncorrected visual acuity in keratoconus patients.

Abstract

BACKGROUND:

Combined excimer laser correction and corneal cross-linking is a promising concept in treating keratoconus patients. Central corneal regularization represents advanced topography-guided custom ablation for ectatic corneas, aiming at correcting irregular astigmatism and at increasing the optical regularity of the corneal surface.

PATIENTS AND METHODS:

In a prospective single centre study, 10 keratoconus patients underwent combined treatment with corneal cross-linking and central corneal regularization by an iRES-Laser. Uncorrected visual acuity at 1 and 3 months postoperatively represented the primary endpoint.

RESULTS:

Mean preoperative uncorrected decimal visual acuity was 0.15 (± 0.28 standard deviation). Mean postoperative visual acuity was 0.28 (± 0.47) at one month and 0.24 (± 0.25) at three months, respectively.

CONCLUSIONS:

Combined corneal cross-linking and central corneal regularization treatment has the potential to achieve a clinically significant improvement of uncorrected visual acuity.

• Authors: C Kaufmann, F Bochmann, P Baenninger, M A Thiel
• Journal: Klinische Monatsblatter fur Augenheilkunde (Klin Monbl Augenheilkd) Vol. 230 Issue 4 Pg. 333-6 (Apr 2013) ISSN: 1439-3999 [Electronic] Germany
• PMID: 23629772 (Publication Type: Clinical Trial, Journal Article)
• Copyright: Georg Thieme Verlag KG Stuttgart · New York.

Chemical References

• Cross-Linking Reagents

Topics

• Adolescent
• Adult
• Combined Modality Therapy (methods)
• Corneal Topography (methods)
• Cross-Linking Reagents (therapeutic use)
• Female
• Humans
• Keratoconus (complications, diagnosis, surgery)
• Keratomileusis, Laser In Situ (methods)
• Lasers, Excimer (therapeutic use)
• Male
• Therapy, Computer-Assisted (methods)
• Treatment Outcome
• Vision Disorders (diagnosis, etiology, surgery)
• Visual Acuity
• Young Adult