Abstract | PURPOSE: DESIGN: Cohort study. METHODS: We recruited 1932 cataract surgical patients aged ≥64 years at Westmead Hospital (2004-2007). The surgical eye of each patient was assessed for presence of cellophane reflex or preretinal fibrosis at preoperative and 1-month-postoperative visits, and annually thereafter, using retinal image grading. Agreement on ERM detection between preoperative and 1-month-postoperative visits was assessed using kappa statistics. Cumulative incidence of ERM from 1 month to 3 years postoperatively was estimated using Kaplan-Meier methods and compared to the 5-year incidence of idiopathic ERM in right eyes of age-matched Blue Mountains Eye Study (BMES) participants. RESULTS: ERM prevalence was 13.9% among 1394 participants with retinal photographs taken 1 month postoperatively. Of 1040 participants with retinal photographs from both preoperative and 1-month-postoperative visits, ERM was detected in 3.1% and 14.8%, respectively, with low diagnostic agreement (kappa = 0.17). Of 1119 subjects without ERM 1 month post surgery, the 3-year cumulative incidence of ERM was 11.2% (95% confidence interval [CI], 9.4%-13.4%; cellophane reflex 6.6%; preretinal fibrosis 4.2%). The age-standardized 3-year incidence of ERM in the surgical cohort (12.1%, 95% CI 8.6%-16.9%) was higher than the 5-year incidence of the BMES subsample (4.4%, 95% CI 3.0%-6.0%). CONCLUSIONS: A substantial under-detection of ERM in eyes before cataract surgery could incorrectly contribute to ERM incidence after surgery. Over 3 years, ERM developed in >10%, including preretinal fibrosis in 4%, of surgical eyes free of ERM 1 month post surgery.
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Authors | Calvin Sze-Un Fong, Paul Mitchell, Elena Rochtchina, Thomas Hong, Tania de Loryn, Jie Jin Wang |
Journal | American journal of ophthalmology
(Am J Ophthalmol)
Vol. 156
Issue 2
Pg. 312-318.e1
(Aug 2013)
ISSN: 1879-1891 [Electronic] United States |
PMID | 23628353
(Publication Type: Journal Article, Research Support, Non-U.S. Gov't)
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Copyright | Copyright © 2013 Elsevier Inc. All rights reserved. |
Topics |
- Aged
- Aged, 80 and over
- Cohort Studies
- Disease Progression
- Epiretinal Membrane
(diagnosis, epidemiology)
- Female
- Follow-Up Studies
- Humans
- Incidence
- Kaplan-Meier Estimate
- Lens Implantation, Intraocular
- Male
- Middle Aged
- New South Wales
(epidemiology)
- Phacoemulsification
- Postoperative Complications
- Prevalence
- Visual Acuity
(physiology)
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