Abstract | PURPOSE: To access efficacy of percutaneous microwave ablation (MWA) of liver metastases from nasopharyngeal carcinoma (NPC). MATERIALS AND METHODS: From March 2007 to June 2012, 18 consecutive patients with NPC and liver metastases (15 men and three women; average age, 45.7 y; age range, 31-61 y) received computed tomography (CT)-guided percutaneous MWA treatment. A total of 27 ablations were performed involving 24 liver metastatic lesions in 18 patients with NPC. Average patient follow-up after ablation was 22.4 months (range, 2-52 mo). The average number of liver metastases per patient was 1.3 (range, 1-4 lesions), with lesion diameters ranging from 1.9 cm to 4.2 cm. Evaluation was then performed to assess percentage of complete necrosis, local tumor progression, and safety. RESULTS: Technical success was achieved in all 27 MWA procedures performed. During follow-up, new metastatic lesions developed in four of 18 patients. Of these, two were liver metastases, and were successfully treated with repeat WMA. Only two major complications were observed: pneumothorax in a patient with an ablation pathway involving the thorax and postprocedural pain in two other patients. A median overall survival time of 41.4 months was observed (range, 2-50 mo); three of 18 patients died during follow-up. CONCLUSIONS: CT-guided MWA is safe and offers an effective treatment alternative for local tumor control in selected patients with liver metastases from NPC.
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Authors | Xin Li, Wei-jun Fan, Liang Zhang, Xiao-ping Zhang, Hua Jiang, Jian-lei Zhang, Hao Zhang |
Journal | Journal of vascular and interventional radiology : JVIR
(J Vasc Interv Radiol)
Vol. 24
Issue 5
Pg. 680-4
(May 2013)
ISSN: 1535-7732 [Electronic] United States |
PMID | 23622039
(Publication Type: Clinical Trial, Journal Article)
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Copyright | Copyright © 2013 SIR. Published by Elsevier Inc. All rights reserved. |
Topics |
- Adult
- Carcinoma
- Catheter Ablation
(methods)
- Female
- Hepatectomy
(methods)
- Humans
- Liver Neoplasms
(diagnostic imaging, secondary, surgery)
- Male
- Microwaves
(therapeutic use)
- Middle Aged
- Nasopharyngeal Carcinoma
- Nasopharyngeal Neoplasms
(diagnostic imaging, surgery)
- Surgery, Computer-Assisted
(methods)
- Tomography, X-Ray Computed
(methods)
- Treatment Outcome
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