Dietary sodium: a therapeutic target in the treatment of hypertension and CKD.

Abstract

Interventional trials of dietary sodium reduction have demonstrated improvements in blood pressure, cardiovascular events, and chronic kidney disease (CKD). Furthermore, public health initiatives to reduce population sodium intake in Finland and Japan have shown similar benefit in blood pressure and stroke reduction. Recent follow-up data from large cohort trials that suggest increased mortality among individuals with lower urinary sodium excretion have generated controversy regarding the optimal sodium intake. This paper reviews the evidence for the reduction of dietary sodium to prevent and manage chronic diseases, including hypertension, cardiovascular disease, and CKD.

• Authors: Sarah Sanghavi, Joseph A Vassalotti
• Journal: Journal of renal nutrition : the official journal of the Council on Renal Nutrition of the National Kidney Foundation (J Ren Nutr) Vol. 23 Issue 3 Pg. 223-7 (May 2013) ISSN: 1532-8503 [Electronic] United States
• PMID: 23611551 (Publication Type: Journal Article, Review)
• Copyright: Copyright © 2013 National Kidney Foundation, Inc. Published by Elsevier Inc. All rights reserved.

Chemical References

• Sodium Chloride, Dietary

Topics

• Blood Pressure (drug effects)
• Cardiovascular Diseases (prevention & control)
• Chronic Disease
• Diet, Sodium-Restricted
• Finland
• Humans
• Hypertension (prevention & control)
• Japan
• Public Health
• Randomized Controlled Trials as Topic
• Renal Dialysis
• Renal Insufficiency, Chronic (prevention & control)
• Sodium Chloride, Dietary (adverse effects)