The potential impact of highly active antiretroviral therapy on the treatment and epidemiology of ranula in human immunodeficiency virus-positive patients.

Abstract

OBJECTIVE:

The study's aim was to assess the potential therapeutic effect of highly active antiretroviral therapy (HAART) on ranulas in human immunodeficiency virus (HIV)-positive patients.

STUDY DESIGN:

The study includes a retrospective observation of 3 patients who were initially part of a prospective study on the comparative effect of HAART on ranulas in 14 HIV-positive patients. These patients were clinically monitored while pursuing the medical treatment with HAART. Neither a fine needle aspiration nor a surgical procedure was performed. Clinical photographs were used for monitoring of any reduction in the ranula size. The effect of HAART on ranula was assessed at 3, 6 and 12 month.

RESULTS:

A complete resolution of the ranula lesion was noticed in the 3 HIV-positive selected patients. These results were observed between 6 and 12 months period.

CONCLUSION:

This study suggests that HAART might present a potential therapeutic effect on ranula in HIV-positive patients.

• Authors: Kabunda Syebele, Thifhelimbilu I Munzhelele
• Journal: Oral surgery, oral medicine, oral pathology and oral radiology (Oral Surg Oral Med Oral Pathol Oral Radiol) Vol. 116 Issue 1 Pg. e32-6 (Jul 2013) ISSN: 2212-4411 [Electronic] United States
• PMID: 23591101 (Publication Type: Case Reports, Journal Article)
• Copyright: Copyright © 2013 Elsevier Inc. All rights reserved.

Topics

• Adult
• Antiretroviral Therapy, Highly Active
• Child
• Child, Preschool
• Female
• HIV Seropositivity (complications, drug therapy)
• Humans
• Ranula (drug therapy, etiology)
• Retrospective Studies
• Salivary Gland Diseases (drug therapy)