Gallstone formation associated with weight reduction.

Abstract

The author presents the case history of an obese patient in whom gallstones developed 5 months after she began a weight-loss program. Conservative management with chenodeoxycholic acid completely resolved cholelithiasis following four months of treatment. Gallstone-formation has traditionally been attributed to supersaturation of bile with cholesterol. However, the author proposes that the formation of gallstones may also be related to a change in gallbladder mechanics stimulated by dieting over an extended period. Recognition of this risk can lead to early diagnosis of gallstones, thus enhancing effective treatment by conservative methods.

• Authors: J L Dickerman
• Journal: The Journal of the American Osteopathic Association (J Am Osteopath Assoc) Vol. 90 Issue 5 Pg. 456-8 (May 1990) ISSN: 0098-6151 [Print] United States
• PMID: 2354967 (Publication Type: Case Reports, Journal Article)

Chemical References

• Chenodeoxycholic Acid

Topics

• Adult
• Chenodeoxycholic Acid (therapeutic use)
• Cholelithiasis (diagnostic imaging, drug therapy, etiology)
• Diet, Reducing (adverse effects)
• Female
• Humans
• Obesity (diet therapy)
• Radiography