Abstract | PURPOSE OF REVIEW: This review summarizes recent key findings relating to the role of the complement system in renal pathology. RECENT FINDINGS: SUMMARY: Complement activation or dysregulation is important in a range of renal pathology and new therapeutic strategies are being developed which may allow rational therapy for these diseases.
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Authors | H Terence Cook |
Journal | Current opinion in nephrology and hypertension
(Curr Opin Nephrol Hypertens)
Vol. 22
Issue 3
Pg. 295-301
(May 2013)
ISSN: 1473-6543 [Electronic] England |
PMID | 23508058
(Publication Type: Journal Article, Review)
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Chemical References |
- Antibodies, Monoclonal, Humanized
- Complement Inactivating Agents
- Complement System Proteins
- eculizumab
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Topics |
- Animals
- Antibodies, Monoclonal, Humanized
(therapeutic use)
- Complement Activation
(drug effects, genetics)
- Complement Inactivating Agents
(therapeutic use)
- Complement System Proteins
(genetics, metabolism)
- Genetic Predisposition to Disease
- Humans
- Kidney
(drug effects, immunology, pathology)
- Kidney Diseases
(drug therapy, genetics, immunology, pathology)
- Mutation
- Phenotype
- Risk Factors
- Treatment Outcome
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