[Staphylococcus saprophyticus isolated from urine culture in outpatients: epidemiology and antimicrobial susceptibility (Label Bio Elbeuf study - November 2007-July 2009)].

Abstract

OBJECTIVE:

The aim of the study was to determine the distribution and the antibiotic susceptibility of Staphylococcus saprophyticus patterns isolated from urine culture in outpatients (population: 57,000, Elbeuf, Normandie, France).

DESIGN:

Prospective study from November 2007 to October 2009 in collaboration with three private medical laboratories. Determination of susceptibility to oxacillin by disk diffusion (cefoxitin, and moxalactam), automated method (Vitek BioMérieux 2) and mecA PCR's detection. Determination of the minimum inhibitory concentration by microbroth dilution for other antibiotics.

RESULTS:

Five thousand and fifty-one bacterial strains isolated, 91 strains of S. saprophyticus (1.8%), 89 in women (2.25%) and two in men (0.18%). S. saprophyticus represented 10.3% and 14.5% of isolates (women respectively aged between 11 and 30; 16 and 20 years); S. saprophyticus is isolated less frequently in winter. mecA PCR detection was positive for two strains. All strains tested were susceptible to ciprofloxacin and furans. Only one strain is resistant to cotrimoxazole.

CONCLUSIONS:

S. saprophyticus is found mostly in women between 11 to 30 years. Cotrimoxazole (after susceptibility testing) is efficient in case of S. saprophyticus's cystitis. Furans (probabilistic treatment) have to be reevaluated because of the potential for serious adverse effects.

• Authors: R Fabre, A Mérens, C Tabone-Ledan, G Epifanoff, J-D Cavallo, I Ternois
• Journal: Pathologie-biologie (Pathol Biol (Paris)) Vol. 61 Issue 2 Pg. 44-8 (Apr 2013) ISSN: 1768-3114 [Electronic] France
• Vernacular Title: Staphylococcus saprophyticus isolés d'examens cytobactériologiques urinaires en ville : épidémiologie et sensibilité aux antibiotiques (étude Label Bio Elbeuf - novembre 2007-juillet 2009).
• PMID: 23498874 (Publication Type: English Abstract, Journal Article)
• Copyright: Copyright © 2012 Elsevier Masson SAS. All rights reserved.

Chemical References

• Anti-Infective Agents
• Oxacillin

Topics

• Adolescent
• Adult
• Aged
• Anti-Infective Agents (pharmacology)
• Child
• Female
• France (epidemiology)
• Humans
• Male
• Microbial Sensitivity Tests
• Middle Aged
• Outpatients (statistics & numerical data)
• Oxacillin (pharmacology)
• Staphylococcal Infections (epidemiology, microbiology, urine)
• Staphylococcus saprophyticus (drug effects, growth & development, isolation & purification)
• Young Adult