This study aims to evaluate the efficacy of the
ozone and
laser application in the management of
pain, swelling, and
trismus after third-molar surgery. Sixty consecutive patients with asymptomatic impacted mandibular third molars were recruited into the study. Patients were randomized into three treatment groups of 20 patients each: two study groups (group 1 = low-level
laser therapy (
LLLT), group 2 = ozone
therapy) and a control group (no-
LLLT or
ozone therapy). Twenty teeth extractions were performed in each group. Evaluations of
postoperative pain, the number of
analgesics tablets taken,
trismus, swelling, and quality of life (Oral Health Impact Profile-14 questionnaire) were made. The sample consisted of 28 female and 32 male patients, whose total mean age was 23.5 ± 3.4 (range, 18-25) years. The
pain level and the number of
analgesics tablets taken were lower in the ozonated and
LLLT applied groups than in the control group. This study showed that
ozone and
low power laser therapies had a positive effect on the patients' quality of life.
Trismus in the
LLLT group was significantly less than in the ozonated and control groups (p = 0.033).
Ozone application showed no superiority in regards of postoperative swelling; however,
LLLT group had significantly lower postoperative swelling. This study demonstrates that
ozone and
laser therapies are useful for the reduction of
postoperative pain and they increase quality of life after third-molar surgery. Although the
ozone therapy had no effect on postoperative swelling and
trismus after surgical removal of impacted lower third molars,
LLLT had a positive effect.