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[Secondary sclerosing cholangitis following liver transplantation: a rare cause for graft failure].

Abstract
We report on a 25-year-old female patient who presented with recurrent cholestasis following liver transplantation due to primary sclerosing cholangitis. Abdominal ultrasound and computed tomography showed intrahepatic bile duct dilatation and stenosis of the common hepatic artery with flow acceleration and decreased resistance index. The patient developed a severe secondary sclerosing cholangitis (SSC) with biliary casts - despite interventional stent placement of the common hepatic artery - thus requiring retransplantation. After prolonged intensive care unit treatment the patient was discharged in a good general condition. This case report describes SSC as a rare cause for graft failure. In unclear cholestasis after liver transplantation SSC has to be considered as the underlying cause.
AuthorsT Voigtländer, T Alten, F Lehner, C P Strassburg, M P Manns, T O Lankisch
JournalZeitschrift fur Gastroenterologie (Z Gastroenterol) Vol. 51 Issue 3 Pg. 296-8 (Mar 2013) ISSN: 1439-7803 [Electronic] Germany
Vernacular TitleSekundär sklerosierende Cholangitis nach Lebertransplantation: Eine seltene Ursache für ein Transplantatversagen.
PMID23487359 (Publication Type: Case Reports, Journal Article)
Copyright© Georg Thieme Verlag KG Stuttgart · New York.
Topics
  • Adult
  • Cholangitis, Sclerosing (diagnosis, etiology)
  • Diagnosis, Differential
  • Female
  • Graft Rejection (diagnosis, etiology)
  • Humans
  • Liver Transplantation (adverse effects, diagnostic imaging)
  • Radiography

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