Multifocal extra-adrenal paraganglioma evaluated with different PET tracers: comparison between 18F-FDG, 18F-DOPA and 68Ga DOTANOC PET/CT.

Abstract

A 40-year-old female patient with suspected multifocal extra-adrenal paraganglioma, on the basis of biochemical, genetic, and conventional imaging data, underwent 18F-FDG, 18F-DOPA and 68Ga DOTANOC PET/CT. FDOPA- and FDG-PET/CT detected a multifocal mediastinal and cervical paraganglioma. 68Ga-DOTANOC PET/CT detected 2 additional lesions compared to the other PET/CT methods. In our case, somatostatin receptor PET/CT with 68Ga-DOTANOC correctly assessed the extent of the disease in a patient with multifocal paraganglioma.

• Authors: Giorgio Treglia, Giuseppe Cardillo, Antonella Stefanelli, Davide Di Franco, Gerard Ngome Enang, Alessandro Giordano, Vittoria Rufini
• Journal: Clinical nuclear medicine (Clin Nucl Med) Vol. 38 Issue 12 Pg. e458-62 (Dec 2013) ISSN: 1536-0229 [Electronic] United States
• PMID: 23486329 (Publication Type: Case Reports, Journal Article)

Chemical References

• 68Ga-DOTANOC
• Organometallic Compounds
• Radioactive Tracers
• Fluorodeoxyglucose F18
• fluorodopa F 18
• Dihydroxyphenylalanine

Topics

• Adult
• Dihydroxyphenylalanine (analogs & derivatives)
• Female
• Fluorodeoxyglucose F18
• Humans
• Multimodal Imaging
• Organometallic Compounds
• Paraganglioma, Extra-Adrenal (diagnostic imaging)
• Positron-Emission Tomography
• Radioactive Tracers
• Tomography, X-Ray Computed