Abstract | OBJECTIVE: MATERIALS AND METHODS: We performed PEI for HCCs in RFA-high risk locations, either alone or in combination with RFA. There were 20 HCCs (1.7 ± 0.9 cm) in 20 patients (PEI group: n = 12; PEI + RFA group: n = 8). We evaluated technical success, local tumor progression and complications in both groups. RESULTS: Technical success was achieved in all HCCs in both groups. During follow-up, local tumor progression was found in 41.7% (5/12) in the PEI group, whereas 12.5% (1/8) for the PEI + RFA group (p = 0.32). Bile duct dilatation was the most common complication, especially when the tumors were in periportal locations; 55% (5/9) in the PEI group and 50% (2/4) in the PEI + RFA group (p = 1.00). One patient in the PEI group developed severe biliary stricture and upstream dilatation that resulted in atrophy of the left hepatic lobe. One patient treated with PEI + RFA developed cholangitis and an abscess. CONCLUSION: Combined PEI and RFA treatment has a tendency to be more effective than PEI alone for managing HCCs in high risk locations, although the difference is not statistically significant. Even though PEI is generally accepted as a safe procedure, it may cause major biliary complications for managing HCCs adjacent to the portal vein.
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Authors | Dong Ik Cha, Min Woo Lee, Hyunchul Rhim, Dongil Choi, Young-sun Kim, Hyo K Lim |
Journal | Korean journal of radiology
(Korean J Radiol)
2013 Mar-Apr
Vol. 14
Issue 2
Pg. 240-7
ISSN: 2005-8330 [Electronic] Korea (South) |
PMID | 23483664
(Publication Type: Journal Article)
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Chemical References |
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Topics |
- Aged
- Aged, 80 and over
- Carcinoma, Hepatocellular
(drug therapy, surgery)
- Catheter Ablation
(methods)
- Chemoembolization, Therapeutic
(methods)
- Disease Progression
- Ethanol
(administration & dosage)
- Female
- Humans
- Liver Neoplasms
(drug therapy, surgery)
- Magnetic Resonance Imaging
- Male
- Middle Aged
- Postoperative Complications
- Retrospective Studies
- Statistics, Nonparametric
- Tomography, X-Ray Computed
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