Retinal and choroidal thickness in myopic anisometropia.

Abstract

PURPOSE:

We compared the retinal thickness (RT) and choroidal thickness (ChT) between the fellow eyes of nonamblyopic myopic anisometropes.

METHODS:

The eyes of 22 nonamblyopic myopic anisometropes (≥ 1 diopter [D] spherical equivalent refraction [SER] anisometropia) were examined using spectral domain optical coherence tomography (SD-OCT). Customized software was used to register, align, and average multiple foveal OCT B-scan images from each subject to enhance image quality. Two independent masked observers manually determined the RT and ChT from each SD-OCT image up to 2.5 mm nasal and temporal to the fovea. Axial length (AXL) was measured using optical low coherence biometry during relaxed accommodation.

RESULTS:

The mean SER anisometropia was 1.74 ± 0.95 D and the mean interocular AXL difference was 0.58 ± 0.41 mm. There was no significant difference in foveal RT between the fellow eyes (P > 0.05). Mean subfoveal ChT was significantly thinner in the more myopic eye (252 ± 46 μm) compared to the fellow, less myopic eye (286 ± 58 μm) (P < 0.001). There was a moderate correlation between the interocular difference in subfoveal ChT and the interocular difference in AXL (r = -0.50, P < 0.01). Asian anisometropes displayed more regionally symmetrical (nasal-temporal) interocular differences in ChT profile compared to Caucasians.

CONCLUSIONS:

RT was similar between the fellow eyes of myopic anisometropes; however, the subfoveal choroid was significantly thinner in the more myopic (longer) eye of this anisometropic cohort. The interocular asymmetry in ChT correlated with the interocular difference in AXL.

• Authors: Stephen J Vincent, Michael J Collins, Scott A Read, Leo G Carney
• Journal: Investigative ophthalmology & visual science (Invest Ophthalmol Vis Sci) Vol. 54 Issue 4 Pg. 2445-56 (Apr 03 2013) ISSN: 1552-5783 [Electronic] United States
• PMID: 23482471 (Publication Type: Journal Article, Research Support, Non-U.S. Gov't)

Topics

• Anisometropia (complications)
• Axial Length, Eye (anatomy & histology)
• Biometry
• Choroid (anatomy & histology)
• Female
• Humans
• Male
• Myopia (complications)
• Organ Size
• Refraction, Ocular (physiology)
• Retina (anatomy & histology)
• Tomography, Optical Coherence
• Vision, Binocular (physiology)
• Young Adult