Abstract | PURPOSE: South Asians have a higher-than-average risk of CHD. The reasons for this are unclear, but physical inactivity and/or poor responsiveness to exercise may play a role. This study compared the effect of prior exercise on postprandial triacylglycerol (TAG), glucose, insulin, interleukin-6, and soluble intercellular adhesion molecule-1 concentrations in South Asian and European men. METHODS: Ten healthy South Asian men (i.e., nine Indian men and one Pakistani man) and 10 healthy European men age 20 to 28 yr completed two 2-d trials (exercise and control) in a randomized crossover design. On the afternoon of day 1 of the exercise trial, participants ran on a treadmill for 60 min at approximately 70% of maximal oxygen uptake. Participants rested on day 1 of the control trial. On day 2 of both trials, participants rested and consumed high-fat (57% of energy content) test meals for breakfast (0 h) and lunch (4 h). Fourteen venous blood samples were collected from a cannula between 0 and 9 h for metabolic measurements. RESULTS: Three-way ANOVA identified higher (P < 0.05) postprandial TAG and insulin concentrations in South Asian versus European men. Exercise lowered postprandial TAG and interleukin-6 and elevated soluble intercellular adhesion molecule-1 concentrations. An interaction effect indicated a greater decrease (22% vs 10%) in TAG area under the concentration versus time curve after exercise in South Asian than in European men. CONCLUSIONS: Postprandial TAG and insulin responses to high-fat meals were elevated in these South Asian men, but acute exercise was equally, if not more, effective for reducing postprandial lipemia in South Asian than in European men.
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Authors | Saravana Pillai Arjunan, Nicolette Claire Bishop, Alvaro Reischak-Oliveira, David John Stensel |
Journal | Medicine and science in sports and exercise
(Med Sci Sports Exerc)
Vol. 45
Issue 7
Pg. 1261-8
(Jul 2013)
ISSN: 1530-0315 [Electronic] United States |
PMID | 23470315
(Publication Type: Comparative Study, Journal Article, Randomized Controlled Trial, Research Support, Non-U.S. Gov't)
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Chemical References |
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Topics |
- Adult
- Analysis of Variance
- Asian People
- Biomarkers
(blood)
- Coronary Disease
(blood, ethnology, etiology, prevention & control)
- Cross-Over Studies
- Diet, High-Fat
- Exercise Test
- Humans
- Hypertriglyceridemia
(complications, ethnology, prevention & control)
- India
(ethnology)
- Male
- Meals
- Pakistan
(ethnology)
- Postprandial Period
(physiology)
- Risk Factors
- Running
(physiology)
- Triglycerides
(blood)
- White People
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