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Treatment of Dowling-Degos disease with fractional Er:YAG laser.

Abstract
Dowling-Degos disease (DDD) is a rare, benign, autosomal dominant disorder characterized by reticulated pigmentation on flexural areas. Recently, a report of successful Er:YAG ablative laser treatment without any adverse effects was issued. A 49-year-old Korean woman presented with numerous small, hyperpigmented macules in a reticular pattern on her face, axillae, and inguinal folds of several years duration. Histologic examination revealed acanthosis with thin elongated rete ridges, basal branching, and widening. She was diagnosed as having DDD and was treated successfully without any adverse effects using a fractional 2,940-nm Er:YAG ablative laser (LOTUSII, Laseroptek, Sungnam, Korea). Er:YAG ablative laser treatment could be an effective treatment modality for DDD, but in Asians, who have darker skins than Caucasians, or in patients with skin lesions on the face, post-inflammatory hyperpigmentation could be problematic after treatment. Fractional Er:YAG ablative laser treatment should be viewed as an alternative therapeutic option for DDD.
AuthorsJeong Hwan Yun, Ji Hoon Kim, Joon Seok Choi, Joo Young Roh, Jong Rok Lee
JournalJournal of cosmetic and laser therapy : official publication of the European Society for Laser Dermatology (J Cosmet Laser Ther) Vol. 15 Issue 6 Pg. 336-9 (Dec 2013) ISSN: 1476-4180 [Electronic] England
PMID23464495 (Publication Type: Case Reports, Journal Article, Research Support, Non-U.S. Gov't)
Topics
  • Female
  • Humans
  • Hyperpigmentation (pathology, surgery)
  • Lasers, Solid-State (therapeutic use)
  • Middle Aged
  • Skin Diseases, Genetic (pathology, surgery)
  • Skin Diseases, Papulosquamous (pathology, surgery)

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