Abstract | HYPOTHESIS: BACKGROUND: In cases in which medical or surgical treatment options are limited because of existing medical problems or advanced age, most patients with acute facial palsy are advised to await spontaneous recovery or are informed that no effective intervention exists. The purpose of this study was to evaluate the effect of botulinum toxin treatment for facial asymmetry in 18 patients after acute facial palsy who could not be optimally treated by medical or surgical management because of severe medical or other problems. METHODS: From 2009 to 2011, nine patients with Bell's palsy, 5 with herpes zoster oticus and 4 with traumatic facial palsy (10 men and 8 women; age range, 22-82 yr; mean, 50.8 yr) participated in this study. Botulinum toxin A ( Botox; Allergan Incorporated, Irvine, CA, USA) was injected using a tuberculin syringe with a 27-gauge needle. The amount injected per site varied from 2.5 to 3 U, and the total dose used per patient was 32 to 68 U (mean, 47.5 +/- 8.4 U). RESULT: After administration of a single dose of botulinum toxin A on the nonparalyzed side of 18 patients with acute facial paralysis, marked relief of facial asymmetry was observed in 8 patients within 1 month of injection. Decreased facial asymmetry and strengthened facial function on the paralyzed side led to an increased HB and SB grade within 6 months after injection. CONCLUSION:
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Authors | Jin Kim |
Journal | Otology & neurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology
(Otol Neurotol)
Vol. 34
Issue 2
Pg. 319-24
(Feb 2013)
ISSN: 1537-4505 [Electronic] United States |
PMID | 23444480
(Publication Type: Journal Article, Research Support, Non-U.S. Gov't)
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Copyright | (C) 2013 Otology & Neurotology, Inc. |
Chemical References |
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Topics |
- Acute Disease
- Adult
- Aged
- Aged, 80 and over
- Bell Palsy
(drug therapy, pathology)
- Botulinum Toxins
(therapeutic use)
- Electrodiagnosis
- Facial Paralysis
(drug therapy, pathology)
- Female
- Functional Laterality
- Herpes Zoster Oticus
(drug therapy, pathology)
- Humans
- Male
- Middle Aged
- Patient Satisfaction
- Surveys and Questionnaires
- Treatment Outcome
- Young Adult
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