Abstract | PURPOSE: METHODS: Between 2004 and 2007, we prospectively enrolled 52 patients with medial compartment knee OA who underwent opening-wedge HTO fixed with locking Puddu plate and xenograft (n = 26) or non-locking Puddu plate and tricalcium phosphate spacer (n = 26). The alignment of the lower limb was assessed by measuring the hip-knee-ankle (HKA) angle. Clinical outcomes were assessed with the Knee Society Score, Western Ontario and McMaster Universities Osteoarthritis Index, SF-36 and European Quality of Life-5 Dimensions scale. All patients were followed up at six weeks and at three, six, 12 and 24 months post-operatively. Clinical outcomes were assessed preoperatively and at 24 months post-operatively. RESULTS: All clinical scores improved significantly in both groups after surgery, without any significant difference between the two groups. Immediately after surgery, the HKA angle went from 9.1 ± 5.2° in varus to 3.1 ± 4.8° in valgus (P = 0.01) in the xenograft group, and from 8.5 ± 5.9° in varus to 3.4 ± 4.2° in valgus (P = 0.01) in the tricalcium phosphate group. At the last follow-up, the tricalcium phosphate group showed a significant loss of correction (P = 0.03). CONCLUSIONS: HTO performed with xenograft locking plate and tricalcium phosphate non-locking plate constructs showed good clinical outcomes. However, the xenograft locking plate construct is superior to the tricalcium phosphate spacer non-locking plate to prevent the loss of correction in the middle term.
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Authors | Nicola Maffulli, Mattia Loppini, Umile Giuseppe Longo, Vincenzo Denaro, Francesco Oliva |
Journal | International orthopaedics
(Int Orthop)
Vol. 37
Issue 5
Pg. 819-26
(May 2013)
ISSN: 1432-5195 [Electronic] Germany |
PMID | 23412369
(Publication Type: Comparative Study, Journal Article)
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Chemical References |
- Calcium Phosphates
- tricalcium phosphate
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Topics |
- Adult
- Aged
- Animals
- Bioprosthesis
- Bone Malalignment
- Bone Plates
- Calcium Phosphates
- Cattle
- Female
- Humans
- Knee Prosthesis
- Male
- Middle Aged
- Osteoarthritis, Knee
(physiopathology, rehabilitation, surgery)
- Osteotomy
(instrumentation, methods, rehabilitation)
- Postoperative Complications
- Prospective Studies
- Prosthesis Design
- Tibia
(surgery)
- Treatment Outcome
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