[Features of anesthesia in rats at abdominal operations].

Abstract

Nowadays, in Russia, diethyl ether is the most popular narcosis for rodent and particular rats. We had tested the new methods based on Zoletil 100 + XylaVet (15 mg/kg and 15-10-5 mg/kg) respectively. 6 conventional female rats were treated with this narcosis. The rats, early have narcotized by diethyl ether were investigated as control group. All of 6 treated with new narcosis animals died in early post-operative time. Interestingly enough, that organ toxicity, except neurologic toxicity, was not described in literature and manuals. We assume that this new narcosis is the cause of portal thromboses.

• Authors: A V Smirnova, L D Lagutina, I E Trubitsina, O S Vasnev, O B Ianova
• Journal: Eksperimental'naia i klinicheskaia gastroenterologiia = Experimental & clinical gastroenterology (Eksp Klin Gastroenterol) Issue 5 Pg. 62-5 ( 2012) ISSN: 1682-8658 [Print] Russia (Federation)
• PMID: 23402173 (Publication Type: English Abstract, Journal Article)

Chemical References

• Anesthetics
• Drug Combinations
• tiletamine, zolazepam drug combination
• Tiletamine
• Zolazepam

Topics

• Anesthesia, General (adverse effects, methods)
• Anesthetics (adverse effects, pharmacology)
• Animals
• Budd-Chiari Syndrome (chemically induced)
• Digestive System Surgical Procedures (adverse effects, methods)
• Drug Combinations
• Female
• Postoperative Complications (chemically induced)
• Rats
• Tiletamine (adverse effects, pharmacology)
• Zolazepam (adverse effects, pharmacology)