Angioedema, elephantiasis nostras, and cheilitis granulomatosa.

Abstract

Angioedema of the face is a common entity seen by the allergist, but other less common conditions should also be considered in the differential diagnosis of facial swelling. Elephantiasis nostras is a rare condition that can result in persistent swelling of the lips secondary to recurrent attacks of lymphangitis caused by bacterial infection. Cheilitis granulomatosa is a disorder that may also present with lip swelling. We present a patient with persistent swelling of his lips who was referred to our service to consider an allergic cause. The clinical findings of persistence of the swelling without improvement after therapy with corticosteroids and antihistamines are considered consistent with elephantiasis nostras or cheilitis granulomatosa. The histopathologic findings in this case revealed epithelioid cell granulomas, which are consistent with cheilitis granulomatosa. These two disorders should be included in the differential diagnosis of localized swelling of the face.

• Authors: J A Cranberg, R Patterson, W A Caro
• Journal: Allergy proceedings : the official journal of regional and state allergy societies (Allergy Proc) 1990 Mar-Apr Vol. 11 Issue 2 Pg. 79-82 ISSN: 1046-9354 [Print] United States
• PMID: 2338241 (Publication Type: Case Reports, Journal Article, Research Support, Non-U.S. Gov't, Research Support, U.S. Gov't, P.H.S.)

Topics

• Adult
• Angioedema (pathology)
• Cheilitis (pathology)
• Diagnosis, Differential
• Elephantiasis (pathology)
• Granuloma (pathology)
• Humans
• Lip (pathology)
• Lymphedema (pathology)
• Male