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[Does the use of TachoSil allow to reduce the morbidity of axillary dissection?].

Abstract
The lymphocele is the most frequently encountered complication after axillary dissection performed for breast cancer (15-81%). This study compares the efficacy of a lympho-hemostatic combipatch TachoSil(®) versus conventional implementation of a suction drain on the incidence and severity of lymphoceles. This is a case (group TachoSil(®)n=20) control (drainage group) n=40 study. In our study, we demonstrated an increased rate of postoperative complications (<3weeks) in the group TachoSil(®) (P=0.0265) explained by a lymphocele rate significantly higher (P=0.0194). However, no significant difference was demonstrated on the severity of these lymphoceles. Beyond 3weeks postoperatively, the two groups were comparable in terms of postoperative complications. The TachoSil(®) does not prevent the formation of seroma but their severity is not increased. In addition, it reduces of more than 48hours the duration of hospitalization stay (P=0.002).
AuthorsC Lacoste, L Ouldamer, G Body, H Marret
JournalGynecologie, obstetrique & fertilite (Gynecol Obstet Fertil) Vol. 41 Issue 2 Pg. 141-3 (Feb 2013) ISSN: 1769-6682 [Electronic] France
Vernacular TitleL'utilisation du TachoSil permet-elle de réduire la morbidité du curage axillaire ?
PMID23375637 (Publication Type: English Abstract, Journal Article)
CopyrightCopyright © 2013 Elsevier Masson SAS. All rights reserved.
Chemical References
  • Drug Combinations
  • TachoSil
  • Fibrinogen
  • Thrombin
Topics
  • Axilla
  • Breast Neoplasms (surgery)
  • Drug Combinations
  • Female
  • Fibrinogen (therapeutic use)
  • Humans
  • Lymph Node Excision (adverse effects, methods)
  • Lymphocele (etiology, prevention & control)
  • Postoperative Complications (prevention & control)
  • Thrombin (therapeutic use)

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