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Secretory endometrium associated with breakthrough bleeding in estrogen-treated postmenopausal women.

Abstract
Paradoxical secretory changes are described in benign endometria curetted for breakthrough bleeding in postmenopausal women on cyclic low dosage Premarin therapy. This purely histologic study, though favoring progesterone mediation, provides no definitive answer to the problem of pathogenesis. Future correlative morphologic and endocrine investigations are clearly indicated.
AuthorsL H Honoré
JournalEuropean journal of obstetrics, gynecology, and reproductive biology (Eur J Obstet Gynecol Reprod Biol) Vol. 7 Issue 3 Pg. 141-5 ( 1977) ISSN: 0301-2115 [Print] Ireland
PMID233742 (Publication Type: Journal Article)
Chemical References
  • Estrogens, Conjugated (USP)
Topics
  • Endometrium (pathology)
  • Estrogens, Conjugated (USP) (administration & dosage)
  • Female
  • Humans
  • Menopause
  • Middle Aged
  • Uterine Hemorrhage (pathology)

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