Sugammadex is a modified
gamma-cyclodextrin which is showing favorable outcomes regarding reversal of neuromuscular blockade, especially by
rocuronium. It is designed to encapsulate
rocuronium and being considered a new class of drugs as selective relaxant binding agents. It has given countless benefits to the patients at risk of incomplete or delayed recovery after neuromuscular block and has renown for another milestone in
anesthesia practice. Recurrence of neuromuscular block has not been reported to be associated with the provided doses of
sugammadex that are adequate for selected for reversal. Acceptable profiles are brought to light telling safety of
sugammadex. However, some questions related to the twitch characteristics those resembled
succinylcholine when reversal, the application for
rocuronium anaphylaxis, and the
hypersensitivity or
anaphylaxis to
sugammadex remain and are need of further investigation. It is imperative that potential problems that we need attention may include the patient's history of
pulmonary disease and allergic disease for using
sugammadex.