Combined infection of vertebroplasty and aortic graft after intravesical BCG treatment.

Abstract

We report a 58-year-old man with spondylodiscitis by Mycobacterium bovis-BCG 3 years after intravesical BCG treatment, and shortly after a vertebroplasty. Further examination showed a psoas abscess and oedema around an endovascular aortic graft, which had been placed 1 year earlier. Puncture of the psoas abscess also grew M bovis-BCG. The patient recovered with a combination of antituberculous treatment and surgery. With hindsight a mycotic aneurysm had been present at the time of aortic graft placement and spondylodiscitis at the time of vertebroplasty. This case shows that low grade and longstanding infections may occur following intravesical BCG installation.

• Authors: Bart Santbergen, P H W E Vriens, W C M de Lange, M E E Van Kasteren
• Journal: BMJ case reports (BMJ Case Rep) Vol. 2013 (Jan 25 2013) ISSN: 1757-790X [Electronic] England
• PMID: 23355584 (Publication Type: Case Reports, Journal Article)

Chemical References

• Antitubercular Agents
• BCG Vaccine

Topics

• Administration, Intravesical
• Antitubercular Agents (therapeutic use)
• Aorta (microbiology)
• Aortic Aneurysm (surgery)
• BCG Vaccine (adverse effects, therapeutic use)
• Carcinoma (drug therapy)
• Humans
• Lumbar Vertebrae (microbiology)
• Male
• Middle Aged
• Mycobacterium bovis
• Psoas Abscess (drug therapy, microbiology)
• Tuberculosis, Cardiovascular (drug therapy, microbiology)
• Tuberculosis, Spinal (drug therapy, microbiology)
• Urinary Bladder Neoplasms (drug therapy)
• Vascular Grafting (adverse effects)
• Vertebroplasty (adverse effects)