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Lymphotoxin β receptor mediates caspase-dependent tumor cell apoptosis in vitro and tumor suppression in vivo despite induction of NF-κB activation.

AuthorsXiaolin Hu, Mary A Zimmerman, Kankana Bardhan, Dafeng Yang, Jennifer L Waller, Georgia B Liles, Jeffrey R Lee, Raphael Pollock, Dina Lev, Carl F Ware, Ellen Garber, Veronique Bailly, Jeffrey L Browning, Kebin Liu
JournalCarcinogenesis (Carcinogenesis) Vol. 34 Issue 5 Pg. 1105-14 (May 2013) ISSN: 1460-2180 [Electronic] England
PMID23349015 (Publication Type: Journal Article, Research Support, N.I.H., Extramural, Research Support, Non-U.S. Gov't)
Chemical References
  • Ligands
  • Lymphotoxin beta Receptor
  • NF-kappa B
  • Tumor Suppressor Proteins
  • Caspases
Topics
  • Animals
  • Apoptosis (physiology)
  • Caspases (genetics, metabolism)
  • Cell Line, Tumor
  • Colonic Neoplasms (genetics, metabolism, pathology)
  • Humans
  • Ligands
  • Lymphotoxin beta Receptor (genetics, metabolism)
  • Mice
  • Mice, Inbred BALB C
  • Mice, Inbred C57BL
  • Mice, Knockout
  • Mitochondria (genetics, metabolism)
  • NF-kappa B (genetics, metabolism)
  • Transplantation, Heterologous
  • Tumor Suppressor Proteins (genetics, metabolism)

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