Aerosolised heparin in the treatment of Fontan-related plastic bronchitis.

Abstract

Patients with Fontan palliation and single-ventricle physiology encounter multiple comorbidities including plastic bronchitis, a disease characterised by the plugging of small and large airways by rubbery, white casts. To date, no controlled clinical trials have demonstrated effective treatment of plastic bronchitis. We report the application of aerosolised heparin, which has published success in non-cardiac-related pulmonary disease, for this complication in a Fontan patient.

• Authors: Daniel E Eason, Kristin Cox, William B Moskowitz
• Journal: Cardiology in the young (Cardiol Young) Vol. 24 Issue 1 Pg. 140-2 (Feb 2014) ISSN: 1467-1107 [Electronic] England
• PMID: 23328485 (Publication Type: Case Reports, Journal Article)

Chemical References

• Aerosols
• Fibrinolytic Agents
• Heparin

Topics

• Administration, Inhalation
• Aerosols
• Bronchitis (complications, drug therapy)
• Child, Preschool
• Female
• Fibrinolytic Agents (therapeutic use)
• Fontan Procedure
• Heart Septal Defects, Ventricular (complications, surgery)
• Heart Ventricles (abnormalities, surgery)
• Heparin (therapeutic use)
• Humans
• Pulmonary Valve Stenosis (complications, surgery)
• Treatment Outcome