HOMEPRODUCTSCOMPANYCONTACTFAQResearchDictionaryPharmaSign Up FREE or Login

Characteristics and outcomes of pediatric out-of-hospital cardiac arrest by scholastic age category.

AbstractOBJECTIVES:
There is a paucity of data examining nationwide population-based incidences and outcomes of pediatric out-of-hospital cardiac arrest. The objective of this study is to describe the detailed characteristics of pediatric out-of-hospital cardiac arrest by scholastic age category and to evaluate the impact of bystander cardiopulmonary resuscitation and public access-automated external defibrillators on the 1-month survival and favorable neurological status of pediatric out-of-hospital cardiac arrest patients.
DESIGN:
A nationwide, population-based, observational study.
SETTING:
Nationwide emergency medical system in Japan.
PATIENTS:
Out-of-hospital cardiac arrest patients aged ≤ 18 yr.
MEASUREMENTS AND MAIN RESULTS:
We identified 7,624 pediatric out-of-hospital cardiac arrest patients (≤ 18 yr old) from a nationwide population-based out-of-hospital cardiac arrest database in Japan from 2005 to 2008 and stratified them into five categories by scholastic age. The overall rates of 1-month survival and favorable neurological outcomes were 11.0% and 5.1%, respectively. Bystander cardiopulmonary resuscitation resulted in a significant improvement in both 1-month survival (odds ratio 2.81; 95% confidence interval 2.30-3.44) and favorable neurological outcomes (odds ratio 4.55; 95% confidence interval 3.35-6.18). Performing public access-automated external defibrillators had a significant effect on the 1-month survival rate (odds ratio 3.51; 95% confidence interval 1.81-6.81) and favorable neurological outcomes (odds ratio 5.13; 95% confidence interval 2.64-9.96).
CONCLUSIONS:
This study demonstrated that bystander cardiopulmonary resuscitation and public access-automated external defibrillators had a significant impact on the outcomes of pediatric out-of-hospital cardiac arrest. The improved survival associated with bystander cardiopulmonary resuscitation and public access-automated external defibrillators are clinically important and are of major public health importance for school-aged out-of-hospital cardiac arrest patients.
AuthorsManabu Akahane, Seizan Tanabe, Toshio Ogawa, Soichi Koike, Hiromasa Horiguchi, Hideo Yasunaga, Tomoaki Imamura
JournalPediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies (Pediatr Crit Care Med) Vol. 14 Issue 2 Pg. 130-6 (Feb 2013) ISSN: 1529-7535 [Print] United States
PMID23314182 (Publication Type: Journal Article, Research Support, Non-U.S. Gov't)
Topics
  • Adolescent
  • Cardiopulmonary Resuscitation
  • Child
  • Child, Preschool
  • Confidence Intervals
  • Defibrillators
  • Electric Countershock
  • Female
  • First Aid
  • Humans
  • Infant
  • Japan
  • Logistic Models
  • Male
  • Nervous System Diseases (etiology)
  • Odds Ratio
  • Out-of-Hospital Cardiac Arrest (complications, etiology, therapy)
  • Survival Rate

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.
Realize the full power of the drug-disease research graph!


Choose Username:
Email:
Password:
Verify Password:
Enter Code Shown: