Hypertension and dyslipidaemia are important components of
metabolic syndrome and both are known to complicate each other. Materials and Methods. A total of 149 subjects consisting of 107 hypertensive patients, grouped into 3 (of 37, 35, and 35 patients categorized based on the grade of
hypertension as grade 1, grade 2, and grade 3, resp.) and 42 controls, were recruited for this study. Each subject had a recording of the bio- and anthropometric data comprising of the age, height,
weight, body mass index (BMI), and abdominal circumference (AC). The blood pressure was also recorded. Fasting blood was collected and serum was used for the estimation of the
lipids: total
cholesterol (TC),
high-density lipoprotein cholesterol (HDL-C), and
triglyceride (TG), while
low density lipoprotein cholesterol (
LDL-C) and VLDL were estimated using Friedewald formula. Findings. Patients with
hypertension had higher
lipid and
lipoprotein levels than the controls and the values became more significant with increasing severity of
hypertension. The difference was statistically significant for TC,
LDL-C, and VLDL-C (P < 0.05). Conclusion. This study showed that
lipid and
lipoprotein cholesterol abnormalities exist and even worsen with severity of
hypertension. It is important that investigations in patients with
hypertension should include a
lipid profile.