Medical dissolution of feline struvite urocystoliths.

Abstract	The efficacy of a diet designed to facilitate dissolution of feline magnesium ammonium phosphate (struvite) uroliths was evaluated in 30 cases of urolithiasis, sterile struvite uroliths dissolved in a mean of 36 days after initiation of dietary treatment. In 5 cases of urolithiasis, struvite urocystoliths associated with urease-negative bacterial urinary tract infection dissolved in a mean of 23 days after initiation of dietary and antimicrobial treatment. In 3 cases of urolithiasis, struvite urocystoliths associated with urease-positive staphylococcal urinary tract infection dissolved in a mean of 79 days after initiation of dietary and antimicrobial treatment. Dissolution of uroliths in cats fed the treatment diet was associated with concomitant remission of dysuria, hematuria, and pyuria, and reduction in urine pH and struvite crystalluria. In one case, a urocystolith composed of 100% ammonium urate, and in another case, a urolith composed of 60% calcium phosphate, 20% calcium oxalate, and 20% magnesium ammonium phosphate did not dissolve.
Authors	C A Osborne, J P Lulich, J M Kruger, D J Polzin, G R Johnston, R A Kroll
Journal	Journal of the American Veterinary Medical Association (J Am Vet Med Assoc) Vol. 196 Issue 7 Pg. 1053-63 (Apr 01 1990) ISSN: 0003-1488 [Print] United States
PMID	2329073 (Publication Type: Journal Article)
Chemical References	Clavulanic Acids Magnesium Compounds Phosphates Amoxicillin-Potassium Clavulanate Combination Amoxicillin Struvite Magnesium
Topics	Amoxicillin (therapeutic use) Amoxicillin-Potassium Clavulanate Combination Animals Cat Diseases (diagnostic imaging, diet therapy) Cats Clavulanic Acids (therapeutic use) Drug Therapy, Combination (therapeutic use) Female Follow-Up Studies Hydrogen-Ion Concentration Magnesium (analysis, urine) Magnesium Compounds Male Phosphates (analysis, urine) Radiography Recurrence Specific Gravity Struvite Time Factors Urinary Calculi (analysis, diagnostic imaging, diet therapy, urine, veterinary) Urinary Tract Infections (complications, drug therapy, veterinary)

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