Abstract | BACKGROUND: METHODS: We retrospectively analyzed all patients with pancreaticobiliary cancer who underwent upper endoscopy with SEMS placement for malignant duodenal obstruction at the National Cancer Center of Korea between April 2003 and December 2010. The technical and clinical success rates of the procedure, complications, and durations of stent patency and overall survival were evaluated. RESULTS: We identified 70 patients with a mean age of 51.2 years (range = 39-81 years); of these, 46 (65.7 %) had pancreatic cancer, 9 (12.9 %) had bile duct cancer, 11 (15.7 %) had gallbladder cancer, and 4 (5.7 %) had cancer of the ampulla of Vater. Twenty-four patients (34.3 %) received covered SEMSs and 46 (65.7 %) received uncovered SEMSs. Technical and clinical success rates were similar for the covered and uncovered stent groups. The complication rate was higher in the covered than in the uncovered group (62.5 vs. 34.8 %, P = 0.025), due primarily to a significantly higher stent migration rate (20.8 vs. 0 %, P = 0.004). Perforation as a late complication occurred in four patients, two in each group (8.3 vs. 4.3 %, P = 0.425). Stent patency tended to be shorter for covered than for uncovered duodenal stents (13.7 ± 8.6 weeks vs. not reached, P = 0.069). CONCLUSIONS: The use of uncovered stents may be a preferred option for duodenal obstruction secondary to pancreaticobiliary malignancies, since they were effective in preventing stent migration and tended to have longer patency than covered stents. Careful attention should be paid to signs and symptoms of perforation during follow-up.
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Authors | Sang Myung Woo, Dong Hwan Kim, Woo Jin Lee, Kyung Woo Park, Sang-Jae Park, Sung-Sik Han, Tae Hyun Kim, Young Hwan Koh, Hyun Bum Kim, Eun Kyung Hong |
Journal | Surgical endoscopy
(Surg Endosc)
Vol. 27
Issue 6
Pg. 2031-9
(Jun 2013)
ISSN: 1432-2218 [Electronic] Germany |
PMID | 23288317
(Publication Type: Comparative Study, Evaluation Study, Journal Article)
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Topics |
- Adult
- Aged
- Aged, 80 and over
- Biliary Tract Neoplasms
(complications, surgery)
- Duodenal Obstruction
(etiology, surgery)
- Female
- Humans
- Male
- Middle Aged
- Pancreatic Neoplasms
(complications, surgery)
- Postoperative Complications
(etiology)
- Retrospective Studies
- Stents
- Treatment Outcome
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