Anetoderma secondary to antiphospholipid antibodies.

Abstract

Anetoderma is an elastolytic disorder that is associated with a number of infectious and autoimmune disorders. We present a case of a patient with generalized anetoderma, who was later found to have positive antinuclear antibodies and antiphospholipid antibodies (APAs). Numerous other cases have been reported in literature and some authors have suggested that anetoderma is a highly specific sign of APAs, with or without other manifestations of systemic lupus erythematosus or antiphospholipid syndrome [14]. Thus, work up for connective-tissue disorders should be considered in any patients who present with this skin finding.

• Authors: John Eungdamrong, Max Fischer, Rishi Patel, Shane Meehan, Miguel Sanchez
• Journal: Dermatology online journal (Dermatol Online J) Vol. 18 Issue 12 Pg. 26 (Dec 15 2012) ISSN: 1087-2108 [Electronic] United States
• PMID: 23286816 (Publication Type: Case Reports, Journal Article)

Chemical References

• Antibodies, Antiphospholipid
• beta 2-Glycoprotein I

Topics

• Anetoderma (diagnosis, immunology)
• Antibodies, Antiphospholipid (blood)
• Humans
• Male
• Middle Aged
• Partial Thromboplastin Time
• Pruritus (etiology)
• beta 2-Glycoprotein I (immunology)