Abstract |
By using immunohistoenzymatic techniques, cells of 4 pituitary adenomas are revealed with beta MSH, alpha and beta endorphins antisera but do not react with 1--24 and 17--39 ACTH antisera. These data suggest that adenomatous cells are able to synthesize and LPH-like molecule without ACTH. The levels of plasmatic LPH and beta MSH, studied by RIA, stay normal. These results are discussed.
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Authors | G Tramu, J C Beauvillain, M Mazzuca, F Girard, E Laine, J L Christiaens, J L Wemeau, P Fossati, M Linquette |
Journal | Annales d'endocrinologie
(Ann Endocrinol (Paris))
Vol. 40
Issue 6
Pg. 561-2
( 1979)
ISSN: 0003-4266 [Print] France |
Vernacular Title | Adénomes hypophysaires avec cellules à bêta MSH et à alpha et bêta endorphines sans ACTH. |
PMID | 232836
(Publication Type: English Abstract, Journal Article)
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Chemical References |
- Endorphins
- Adrenocorticotropic Hormone
- Melanocyte-Stimulating Hormones
- beta-Lipotropin
|
Topics |
- Adenoma
(analysis)
- Adolescent
- Adrenocorticotropic Hormone
(analysis)
- Adult
- Endorphins
(analysis)
- Female
- Histocytochemistry
- Humans
- Immunoenzyme Techniques
- Melanocyte-Stimulating Hormones
(analysis, blood)
- Microscopy, Electron
- Middle Aged
- Pituitary Neoplasms
(analysis)
- beta-Lipotropin
(blood)
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