The use of intravenous streptokinase (SK) in a peripheral hospital in the treatment of acute myocardial infarction.

Abstract

We report our early experience in the use of intravenous Streptokinase in acute coronary occlusion in a peripheral hospital. From 1st November 1988 to 20th July 1989, 30 patients were treated with Streptokinase. The hospital mortality was 1/30 (3.3%) from a non-streptokinase related event. The commonest complication following streptokinase infusion was transient hypotension, affecting 10/30 patients. From a total of 30 patients, 3 had transient bleeding complications and was self limiting. Follow up coronary angiograms were performed on 17/30 patients, demonstrating a patent infarct related artery in 12/17 patients (70.6%). We concluded that it is both feasible and safe to use intravenous streptokinase in a peripheral setting in the treatment of acute myocardial infarction.

• Authors: G Chia, N S Chan, P K Mah, L S Chew, A T Tan
• Journal: Annals of the Academy of Medicine, Singapore (Ann Acad Med Singap) Vol. 19 Issue 1 Pg. 27-9 (Jan 1990) ISSN: 0304-4602 [Print] Singapore
• PMID: 2327718 (Publication Type: Journal Article)

Chemical References

• Streptokinase

Topics

• Adult
• Aged
• Female
• Follow-Up Studies
• Heart Failure (therapy)
• Hospitals, Satellite
• Humans
• Infusions, Intravenous
• Male
• Middle Aged
• Myocardial Infarction (mortality, therapy)
• Shock, Cardiogenic (therapy)
• Singapore (epidemiology)
• Streptokinase (administration & dosage)
• Survival Rate