Abstract | PURPOSE: METHODS: The patient's clinical history, including visual acuity, refractive error, ocular alignment, fundus examination, and optic nerve photographs, was retrospectively reviewed. A literature review was performed for acquired MRNF in children using PubMed. The results of the demographic and clinical findings of our patient were compared with those of previously reported cases. RESULTS: The child developed bilateral MRNF adjacent to the optic nerve 5 months after unilateral ONSF. In reviewing the literature, 8 of 10 cases of acquired MRNF in children had previous abnormalities of the optic nerve, 4 of 10 had associated bilateral optic nerve head drusen, 3 of 10 had associated optic nerve glioma, and 3 of 10 had a history of significant increased intracranial pressure requiring surgical intervention. CONCLUSIONS: Although the etiology of acquired MRNF is uncertain, this case plus a review of the literature suggest that it may be related to changes in the lamina cribosa combined with possible optic nerve injury caused by optic nerve head drusen, optic nerve glioma, or increased intracranial pressure and that it can occur months to years after intervention.
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Authors | Sasapin G Prakalapakorn, Edward G Buckley |
Journal | Journal of AAPOS : the official publication of the American Association for Pediatric Ophthalmology and Strabismus
(J AAPOS)
Vol. 16
Issue 6
Pg. 534-8
(Dec 2012)
ISSN: 1528-3933 [Electronic] United States |
PMID | 23237749
(Publication Type: Case Reports, Journal Article, Research Support, N.I.H., Extramural, Research Support, Non-U.S. Gov't)
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Copyright | Copyright © 2012 American Association for Pediatric Ophthalmology and Strabismus. Published by Mosby, Inc. All rights reserved. |
Topics |
- Decompression, Surgical
(adverse effects)
- Female
- Follow-Up Studies
- Humans
- Infant
- Intracranial Pressure
- Magnetic Resonance Imaging
- Nerve Fibers, Myelinated
(pathology)
- Optic Nerve
(surgery)
- Optic Nerve Diseases
(etiology)
- Papilledema
(diagnosis, surgery)
- Pseudotumor Cerebri
(diagnosis, surgery)
- Retinal Ganglion Cells
(pathology)
- Retrospective Studies
- Visual Acuity
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