Abstract | BACKGROUND: METHODS: Sixty patients who had received ERBD or PTBD for the palliative treatment of obstructive jaundice caused by unresectable HCC between January 2006 and May 2010 were included in this retrospective study. Successful drainage, drainage patency, and the overall survival of patients were evaluated. RESULTS: Univariate analysis revealed that the overall frequency of successful drainage was higher in the ERBD group (22/29, 75.9%) than in the PTBD group (15/31, 48.4%) (P=0.029); but multivariate analysis showed marginal significance (P=0.057). The duration of drainage patency was longer in the ERBD group than in the PTBD group (82 vs 37 days, respectively, P=0.020). Regardless of what procedure was performed, the median survival time of patients who had a successful drainage was much longer than that of the patients who did not have a successful drainage (143 vs 38 days, respectively, P<0.001). CONCLUSION: Besides PTBD, ERBD may be used as the initial treatment option to improve obstructive jaundice in patients with unresectable HCC if there is a longer duration of drainage patency after a successful drainage.
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Authors | Jongkyoung Choi, Ji Kon Ryu, Sang Hyub Lee, Dong-Won Ahn, Jin-Hyeok Hwang, Yong-Tae Kim, Yong Bum Yoon, Joon Koo Han |
Journal | Hepatobiliary & pancreatic diseases international : HBPD INT
(Hepatobiliary Pancreat Dis Int)
Vol. 11
Issue 6
Pg. 636-42
(Dec 15 2012)
ISSN: 1499-3872 [Print] Singapore |
PMID | 23232636
(Publication Type: Comparative Study, Journal Article)
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Topics |
- Aged
- Biliary Tract Surgical Procedures
(adverse effects)
- Carcinoma, Hepatocellular
(complications)
- Chi-Square Distribution
- Drainage
(methods)
- Endoscopy, Digestive System
(adverse effects)
- Female
- Humans
- Jaundice, Obstructive
(etiology, surgery)
- Kaplan-Meier Estimate
- Liver Neoplasms
(complications)
- Male
- Middle Aged
- Multivariate Analysis
- Proportional Hazards Models
- Retrospective Studies
- Stents
- Treatment Outcome
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