The efficacy of 8% Arginine-CaCO₃ applications on dentine hypersensitivity following periodontal therapy: a clinical and scanning electron microscopic study.

Abstract

OBJECTIVES:

Periodontal therapy is one of the etiological factors of dentine hypersensitivity (DH). This study aimed to evaluate the efficacy of %8Arginine-CaCO₃ on DH that affects patients after periodontal treatment.

STUDY DESIGN:

Seventy-one teeth from the volunteers (n=36) with history of DH caused by periodontal therapy were included in this study, and randomly divided into two groups: group-1, who received 8%Arginine-CaCO₃ and group-2, who received 1.23%NaF-gel. The clinical indices were recorded at first visit.DH was evaluated by using tactile, air-blast, and thermal stimuli. The subject's response was recorded at baseline, immediately (Day-0) and one month after the application.

RESULTS AND CONCLUSIONS:

The results were statistically analyzed, and it was found that 8% Arginine-CaCO₃ treatment was more effective than 1.23% NaF-gel at time intervals. Sensitivity score differences between the groups were statistically significant at Day-28. The 8% Arginine-CaCO₃ group exhibited statistically significant reduction in DH on three stimuli at baseline to Day-28. It was concluded that 8% Arginine-CaCO₃ is more effective than 1.23% NaF-gel in reduction of patients' pain.

• Authors: Ahu Uraz, Özge Erol-Şimşek, Selcen Pehlivan, Zekiye Suludere, Belgin Bal
• Journal: Medicina oral, patologia oral y cirugia bucal (Med Oral Patol Oral Cir Bucal) Vol. 18 Issue 2 Pg. e298-305 (Mar 01 2013) ISSN: 1698-6946 [Electronic] Spain
• PMID: 23229241 (Publication Type: Journal Article, Randomized Controlled Trial)

Chemical References

• Drug Combinations
• Arginine
• Calcium Carbonate

Topics

• Adult
• Arginine (administration & dosage)
• Calcium Carbonate (administration & dosage)
• Dentin Sensitivity (drug therapy, pathology)
• Double-Blind Method
• Drug Combinations
• Female
• Humans
• Microscopy, Electron, Scanning
• Periodontal Diseases (therapy)