Incidence of retinopathy of prematurity and risk factors among premature infants at a neonatal intensive care unit in Canada.

Abstract

PURPOSE:

To study the incidence of retinopathy of prematurity (ROP) in a neonatal intensive care unit and obtain information on risk factors associated with ROP.

METHODS:

Four hundred twenty-three infants were screened for ROP between July 2006 and July 2010. Demographic information, clinical data, and risk factors were reviewed.

RESULTS:

The incidence was 40.4% (171 infants) for ROP, 9.2% (39 infants) for severe ROP, and 5.67% (24 infants) for laser treatment. Mean gestational age and birth weight were significantly lower among infants with ROP versus those without ROP (26 ± 0.13 vs 28.55 ± 0.12 weeks, P < .0001 and 840.5 ±17.49 vs 1,190.24 ± 20.20 g, P < .0001, respectively). Birth weight (P < .001), gestational age (P < .001), mechanical ventilation therapy (P = .039), and necrotizing enterocolitis (P = .019) were independent risk factors for ROP.

CONCLUSION:

Gestational age and birth weight were the most significant risk factors for developing ROP. The study population had an elevated percentage of infants with birth weight less than 1,000 g (extremely low birth weight), yet there was no corresponding increase in severe ROP incidence and treatment when compared to other studies.

• Authors: Gloria Isaza, Sourabh Arora, Manpartap Bal, Varun Chaudhary
• Journal: Journal of pediatric ophthalmology and strabismus (J Pediatr Ophthalmol Strabismus) 2013 Jan-Feb Vol. 50 Issue 1 Pg. 27-32 ISSN: 1938-2405 [Electronic] United States
• PMID: 23205771 (Publication Type: Journal Article)
• Copyright: Copyright 2013, SLACK Incorporated.

Topics

• Birth Weight
• Canada (epidemiology)
• Gestational Age
• Humans
• Incidence
• Infant, Extremely Low Birth Weight
• Infant, Low Birth Weight
• Infant, Newborn
• Infant, Premature
• Infant, Very Low Birth Weight
• Intensive Care Units, Neonatal (statistics & numerical data)
• Laser Coagulation
• Respiration, Artificial
• Retinopathy of Prematurity (epidemiology, surgery)
• Retrospective Studies
• Risk Factors