[Experiences with oxytetracycline treatment of non-gonorrhea urethritis caused by Ureaplasma urealyticum].

Abstract

In a retrospective study, the efficacy of tetracycline therapy was assessed in 48 men with non-gonococcal urethritis who only harbored Ureaplasma urealyticum in their urethras. After 2 weeks of therapy with 2.0 g oxytetracycline per day, U. urealyticum was still found in the urethra of 8 patients (17%). Urethritis was still present in 8 patients (17%) according to clinical criteria and in 11 patients (23%) according to microscopic findings. The persistence of U. urealyticum in the urethra did not correlate with the persistence of urethritis to a statistically significant degree. Therapy compliance, antibiotic resistance in a few cases, reinfections in 2 cases and a special host-parasite relationship are discussed with respect to the treatment failures.

• Authors: P Elsner, A A Hartmann, G Burg
• Journal: Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete (Hautarzt) Vol. 41 Issue 2 Pg. 94-7 (Feb 1990) ISSN: 0017-8470 [Print] Germany
• Vernacular Title: Erfahrungen mit der Oxytetrazyklin-Therapie der nicht-gonorrhoischen Urethritis durch Ureaplasma urealyticum.
• PMID: 2318645 (Publication Type: English Abstract, Journal Article, Research Support, Non-U.S. Gov't)

Chemical References

• Oxytetracycline

Topics

• Adolescent
• Adult
• Humans
• Male
• Middle Aged
• Mycoplasmatales Infections (drug therapy, microbiology)
• Oxytetracycline (administration & dosage)
• Retrospective Studies
• Ureaplasma (drug effects, isolation & purification)
• Urethritis (drug therapy, microbiology)