Biomineralization-based virus shell-engineering: towards neutralization escape and tropism expansion.

Abstract

Biomineralization-based virus shell-engineering (BVSE) is a potential surface modification strategy to afford a biocompatible and biodegradable calcium phosphate (CaPi) shell onto single virus, allowing development of Trojan virus with enhanced infection, expanded tropism and neutralization escape, which open up the multiple applications of virus in biomedicines and materials.

• Authors: Xiaoyu Wang, Yongqiang Deng, Shihua Li, Guangchuan Wang, Ede Qin, Xurong Xu, Ruikang Tang, Chengfeng Qin
• Journal: Advanced healthcare materials (Adv Healthc Mater) Vol. 1 Issue 4 Pg. 443-9 (Jul 2012) ISSN: 2192-2640 [Print] Germany
• PMID: 23184775 (Publication Type: Journal Article, Research Support, Non-U.S. Gov't)
• Copyright: Copyright © 2012 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

Chemical References

• Biocompatible Materials
• Calcium Phosphates
• Minerals
• calcium phosphate

Topics

• Adenoviridae (chemistry, genetics, ultrastructure)
• Biocompatible Materials (chemistry)
• Calcium Phosphates (chemistry)
• Capsid (chemistry, physiology, ultrastructure)
• Genetic Engineering (methods)
• Minerals (chemistry)
• Viral Tropism (physiology)